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Nonlinear Mixed-Effects and Full Bayesian Population Pharmacokinetic Analysis of Ceftolozane–Tazobactam in Critically Ill Patients

2026-03-26

Abstract excerpt

Pharmacokinetic studies in critically ill patients are often constrained by small sample sizes, limiting the strength and generalizability of conclusions drawn solely from observed data. Bayesian inference offers a powerful strategy to address this challenge by incorporating prior knowledge. In this study, we evaluated two model-based approaches for characterizing the population pharmacokinetics of ceftolozane and...

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Literature Corpus work
db427c64-ccfd-542a-b474-44ce3ff43e94
DOI
10.64898/2026.03.24.713879
Open publication

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Nonlinear Mixed-Effects and Full Bayesian Population Pharmacokinetic Analysis of Ceftolozane–Tazobactam in Critically Ill PatientsDOI 10.64898/2026.03.24.713879
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