Article

Interrogation of the Perturbed Gut Microbiota in Gouty Arthritis Patients Through<i>in silico</i>Metabolic Modeling

2020-09-03

Abstract excerpt

Recent studies have shown perturbed gut microbiota associated with gouty arthritis, a metabolic disease in which an imbalance between uric acid production and excretion leads to the deposition of uric acid crystals in joints. To mechanistically investigate altered microbiota metabolism in gout disease, 16S rRNA gene amplicon sequence data from stool samples of gout patients and healthy controls were computationall...

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Literature Corpus work: db149a92-dc8d-5d36-8793-dac1e5e11561
DOI: 10.1101/2020.09.02.20187013

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