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Interrogation of the perturbed gut microbiota in gouty arthritis patients through in silico metabolic modeling

9 Jun 2021

Abstract excerpt

Abstract Recent studies have shown perturbed gut microbiota associated with gouty arthritis, a metabolic disease characterized by an imbalance between uric acid production and excretion. To mechanistically investigate altered microbiota metabolism associated with gout disease, 16S rRNA gene amplicon sequence data from stool samples of gout patients and healthy controls were computationally analyzed through...

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PMID: 34257630
DOI: 10.1002/elsc.202100003

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