Article

Longitudinal transcriptome-wide gene expression analysis of sleep deprivation treatment shows involvement of circadian genes and immune pathways

2019-05-10

Abstract excerpt

<h4>Background</h4> Therapeutic sleep deprivation (SD) rapidly induces robust, transient antidepressant effects in a large proportion of major mood disorder patients suffering from a depressive episode, but underlying biological factors remain poorly understood. Research suggests that these patients may have altered circadian molecular genetic ‘clocks’ and that SD functions through ‘resetting’ dysregulated genes;...

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Literature Corpus work: daebd2a9-9be4-5915-b27c-8cf22d90cda2
DOI: 10.1101/628172

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