Article

Terminal type-specific cannabinoid CB1 receptor alterations in patients with schizophrenia: a pilot study

2023-04-11

Abstract excerpt

<h4>Background</h4> Individuals with schizophrenia are at elevated genetic risks for comorbid cannabis use, and often experience exacerbations of cognitive and psychotic symptoms when exposed to cannabis. These findings have led a number of investigators to examine cannabinoid CB1 receptor (CB1R) alterations in schizophrenia, though with conflicting results. We recently demonstrated the presence of CB1R in both e...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: dad0b08c-b97b-51d4-9275-64252ab12180
DOI: 10.1101/2023.04.11.536217

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Terminal type-specific cannabinoid CB1 receptor alterations in patients with schizophrenia: a pilot studyDOI 10.1101/2023.04.11.536217Read

Cell type specific cannabinoid CB1 receptor distribution across the human and non-human primate cortexSemantic proximity Read

Binding of a tritiated inverse agonist to cannabinoid CB1 receptors is increased in patients with schizophrenia.Semantic proximity Read

Role of cannabis and endocannabinoids in the genesis of schizophrenia.Semantic proximity Read

In Vivo Availability of Cannabinoid 1 Receptor Levels in Patients With First-Episode PsychosisSemantic proximity Read

Association of Cannabis Use during Adolescence, Prefrontal CB1 Receptor Signaling, and SchizophreniaSemantic proximity Read

Allele-specific differences in activity of a novel cannabinoid receptor 1 (CNR1) gene intronic enhancer in hypothalamus, dorsal root ganglia, and hippocampus.Semantic proximity Read

Cannabinoid receptor 1 gene polymorphisms and marijuana misuse interactions on white matter and cognitive deficits in schizophrenia.Semantic proximity Read

New Perspectives in the Studies on Endocannabinoid and Cannabis: Cannabinoid Receptors and SchizophreniaSemantic proximity Read

Cannabinoids and psychosis.Semantic proximity Read

A preliminary study of endocannabinoid system regulation in psychosis: Distinct alterations of CNR1 promoter DNA methylation in patients with schizophreniaSemantic proximity Read

Brain cannabinoid CB2 receptor in schizophrenia.Semantic proximity Read

Human cannabinoid receptor 1: 5' exons, candidate regulatory regions, polymorphisms, haplotypes and association with polysubstance abuse.Semantic proximity Read