Article

Benchmarking Cell-Type-Specific Spatially Variable Gene Detection Methods Using a Realistic and Decomposable Simulation Framework

2025-12-01

Abstract excerpt

Identifying spatially variable genes within individual cell types is essential for characterizing spatially organized cell states and microenvironments from spatial transcriptomics data. Several computational methods have been developed for identifying cell-type-specific spatially variable genes (ctSVGs), but their relative performance and practical utility under realistic biological complexity remain largely unkn...

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Literature Corpus work: da85cbee-2e6b-56d6-af74-6c6df72b0b48
DOI: 10.1101/2025.11.26.690782

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