Back to search

Article

The landscape of longevity across phylogeny

2020-03-18

Abstract excerpt

Lifespan of model organisms can be extended by genetic, dietary and pharmacological interventions, but these effects may be negated by other factors. To understand robustness of longevity interventions within and across species, we analyzed age-dependent mortality of yeast, fruit flies, nematodes and mice subjected to thousands of genetic, pharmacological or dietary interventions, and applied the principles learne...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
da75e844-9f41-5082-abbe-8724808ec735
DOI
10.1101/2020.03.17.995993
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The landscape of longevity across phylogenyDOI 10.1101/2020.03.17.995993
Select a neighboring publication to make it the new centre.