Article

Web-Based Application For Predicting Potential Target Phenotype For Recombinant Human Thrombomodulin Therapy In Patients With Sepsis: Analysis Of Three Multicentre Registries

2022-03-10

Abstract excerpt

A recent randomised controlled trial (RCT) failed to demonstrate a beneficial effect of recombinant human thrombomodulin (rhTM) on sepsis, but there is controversy in the effects of rhTM for sepsis due to heterogeneity of its study population. While we previously identified a distinct phenotype that could be a potential target of rhTM therapy, the discovery of phenotypes itself is insufficient because rules or pre...

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Literature Corpus work: da2bcd46-9daf-5dae-8db6-670f3f92ecef
DOI: 10.21203/rs.3.rs-1425804/v1

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