Article

Exosome based multivalent vaccine: achieving potent immunization, broadened reactivity, and strong T cell responses with nanograms of proteins

2023-01-11

Abstract excerpt

<h4>ABSTRACT</h4> Current approved vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have focused solely on the spike protein to provide immunity. The first vaccines were developed rapidly using spike mRNA delivered by lipid nanoparticles but required ultra-low storage and have had limited immunity against variations in spike. Subsequently, protein-based vaccines were developed which o...

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Literature Corpus work: ea5ad6d2-9d3e-58ca-aadb-b7d06529672f
DOI: 10.1101/2023.01.10.523356

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