Article

Normative Speech Modeling for ALS Diagnosis with Application to Other Neurodegenerative Diseases

2026-05-27

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease affecting more than 450,000 individuals worldwide and is frequently diagnosed more than 12 months after symptom onset, delaying intervention during a critical early window. Because up to 80% of patients develop dysarthria within two years, subtle changes in speech provide a signal of early bulbar motor neuron degeneration. However, exis...

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Literature Corpus work: da11bcb2-14ef-545d-aba7-526b006233f3
DOI: 10.64898/2026.05.25.26354057

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