Article

Searching for influencers among placental immune cells in preeclampsia

2025-03-10

Abstract excerpt

Cells in maternal and fetal immune systems may communicate, leading to immune tolerance during pregnancy; however, this hypothesis remains controversial. Here, we profiled single-cell transcriptional signatures in placental layers comprising the maternal–fetal interface and deep placenta, then searched for genes associated with preeclampsia. To investigate the underlying principle of the failure of immune toleranc...

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Literature Corpus work: d9efdaa3-a0c0-5649-9f10-7ef48402ec27
DOI: 10.1101/2025.03.04.641363

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