Article

The Sponge Hypothesis of Sarcopenia: Functional Hyponatremia and the Liver–Muscle–Fluid Axis in Chronic Liver Disease

2025-12-08

Abstract excerpt

<h4>Summary</h4> <h4>Background & Aims</h4> Dilutional hyponatremia and sarcopenia (SP) are prognostic factors linked to portal hypertension (PHT) in chronic liver disease (CLD). Because skeletal muscle functions as the body’s largest intracellular water reservoir, early Na decline may reflect impaired muscular buffering rather than renal Na loss. This MRIbased study investigated the relationship between serum N...

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Literature Corpus work: d9d20faf-438a-508f-85ea-bca87a55a573
DOI: 10.64898/2025.12.06.25341772

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