Article

Systemic drivers and molecular mechanisms of sarcopenia in aetiology-specific end-stage liver disease

2025-08-25

Abstract excerpt

<h4>Introduction</h4> Patients with end-stage liver disease (ESLD) often present with sarcopenia, defined as loss of skeletal muscle mass and quality, which is associated with reduced quality of life and increased mortality. However, the molecular mechanisms driving sarcopenia in ESLD are not fully understood and there are currently no therapeutic interventions. This study aimed to identify potential circulating...

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Literature Corpus work: 2feb0c5b-49a2-5567-9f9e-8cd1c58d2a87
DOI: 10.1101/2025.08.21.671433

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