Article

Prognostic Insights from Longitudinal Multicompartment Study of Host-Microbiota Interactions in Critically Ill Patients

2023-09-26

Abstract excerpt

Critical illness can disrupt the composition and function of the microbiome, yet comprehensive longitudinal studies are lacking. We conducted a longitudinal analysis of oral, lung, and gut microbiota in a large cohort of 479 mechanically ventilated patients with acute respiratory failure. Progressive dysbiosis emerged in all three body compartments, characterized by reduced alpha diversity, depletion of obligate a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d97c5af4-a06f-5623-bacc-a2483fc9e99d
DOI: 10.1101/2023.09.25.23296086

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Prognostic Insights from Longitudinal Multicompartment Study of Host-Microbiota Interactions in Critically Ill PatientsDOI 10.1101/2023.09.25.23296086Read

Prognostic Insights from Longitudinal Multicompartment Study of Host-Microbiota Interactions in Critically Ill Patients.Semantic proximity Read

Longitudinal multicompartment characterization of host-microbiota interactions in patients with acute respiratory failureSemantic proximity Read

Respiratory Tract Dysbiosis Is Associated with Worse Outcomes in Mechanically Ventilated Patients.Semantic proximity Read

Lung Microbiome in Critically Ill PatientsSemantic proximity Read

The Gut-Lung Axis in Critical Illness: Microbiome Composition as a Pr edictor of Mortality at Day 28 in Mechanically Ventilated PatientsSemantic proximity Read

Altered Ecology of the Respiratory Tract Microbiome and Nosocomial PneumoniaSemantic proximity Read

Gut Microbiome Dynamics and Associations with Mortality in Critically Ill PatientsSemantic proximity Read

Dysbiosis Across Multiple Body Sites in Critically Ill Adult Surgical PatientsSemantic proximity Read

Molecular Accounting and Profiling of Human Respiratory Microbial Communities: Toward Precision Medicine by Targeting the Respiratory Microbiome for Disease Diagnosis and TreatmentSemantic proximity Read

Respiratory Fungal Communities are Associated with Systemic Inflammation and Predict Survival in Patients with Acute Respiratory FailureSemantic proximity Read

The role of the microbiota in the management of intensive care patientsSemantic proximity Read

Composition and dynamics of the respiratory tract microbiome in intubated patients.Semantic proximity Read