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The genetic analysis of a founder Northern American population of European descent identifies<i>FANCI</i>as a candidate familial ovarian cancer risk gene

2020-05-08

Abstract excerpt

Some familial ovarian cancer (OC) could be due to rare risk alleles in genes that each account for a relatively small proportion of cases not due to BRCA1 and BRCA2 , major risk genes in the homologous recombination (HR) DNA repair pathway. We report a new candidate OC risk allele, FANCI c.1813C>T in a Fanconi anemia (FA) gene that plays a role upstream of the HR DNA repair pathway. This variant was identified by...

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Identifiers and source

Literature Corpus work
d96bfb7f-d4bd-5f92-858e-e912f6a35edd
DOI
10.1101/2020.05.04.20090407
Open publication

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The genetic analysis of a founder Northern American population of European descent identifies<i>FANCI</i>as a candidate familial ovarian cancer risk geneDOI 10.1101/2020.05.04.20090407
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