Article

Physical Activity in High-Risk Women reduces Breast Cancer Risk: UK Biobank Study

2026-02-23

Abstract excerpt

<title>Abstract</title> <p> Purpose Physical activity (PA) is associated with reduced breast cancer (BC) risk in average-risk women. Its effect on genetically predisposed high-risk women remains unclear. Methods BC cases (n = 17,409) and controls (n = 26,907) were identified from the UK Biobank with BC-related Polygenic risk score (PRS) and/or pathogenic variants (PVs) in cancer susceptibility genes (CSG), Int...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d965c55d-5346-585f-b7da-773207f99769
DOI: 10.21203/rs.3.rs-8862660/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Physical Activity in High-Risk Women reduces Breast Cancer Risk: UK Biobank StudyDOI 10.21203/rs.3.rs-8862660/v1Read

Association of Nongenetic Factors With Breast Cancer Risk in Genetically Predisposed Groups of Women in the UK Biobank Cohort.Semantic proximity Read

BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors.Semantic proximity Read

Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study.Semantic proximity Read

Accelerometer-measured intensity-specific physical activity, genetic susceptibility, and back pain risk: a UK Biobank cohort study.Semantic proximity Read

Genetic Factors, Adherence to Healthy Lifestyle Behavior, and Risk of Invasive Breast Cancer Among Women in the UK Biobank.Semantic proximity Read

Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis.Semantic proximity Read

Recreational Physical Activity and Outcomes After Breast Cancer in Women at High Familial Risk.Semantic proximity Read

Physical activity and Alzheimer's disease risk across genetic susceptibility: a prospective UK Biobank study using accelerometer data.Semantic proximity Read

Genetic Predisposition to Excess Body Weight and Survival in Women Diagnosed With Breast Cancer.Semantic proximity Read

Physical Activity and Breast Cancer: Focusing on High-Risk Subgroups and Putting Recommendations in Context.Semantic proximity Read

Genome-wide association study of habitual physical activity in over 277,000 UK Biobank participants identifies multiple variants including <i>CADM2</i> and <i>APOE</i>Semantic proximity Read

Blood DNA methylation and breast cancer risk: a prospective nested case-control study.Semantic proximity Read