Article

Single cell analysis of menstrual endometrial tissues defines phenotypes associated with endometriosis

2022-02-15

Abstract excerpt

<h4>Background</h4> Endometriosis is a common, complex disorder which is underrecognized and subject to prolonged delays in diagnosis. It is accompanied by significant changes in the eutopic endometrial lining. <h4>Methods</h4> We have undertaken the first single cell RNA-sequencing (scRNA-Seq) comparison of endometrial tissues in freshly collected menstrual effluent (ME) from 33 subjects, including confirmed en...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d9619f8e-af3c-5530-b9ff-0287499df015
DOI: 10.1101/2022.02.10.22270810

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Single cell analysis of menstrual endometrial tissues defines phenotypes associated with endometriosisDOI 10.1101/2022.02.10.22270810Read

Single-cell analysis of menstrual endometrial tissues defines phenotypes associated with endometriosis.Semantic proximity Read

Single-Cell Profiling Reveals Altered Endometrial Cellular Features Across the Menstrual Cycle in Endometriosis PatientsSemantic proximity Read

Cellular heterogeneity and dynamics of the human uterus in healthy premenopausal womenSemantic proximity Read

Single-cell analysis of endometrial proliferation and secretory phases in patients with endometriosis and normal populationSemantic proximity Read

Integrating endometrial proteomic and single cell transcriptomic pipelines reveals distinct menstrual cycle and endometriosis-associated molecular profilesSemantic proximity Read

Analysis of menstrual effluent: diagnostic potential for endometriosis.Semantic proximity Read

Single-cell transcriptomic analysis of endometriosis provides insights into fibroblast fates and immune cell heterogeneitySemantic proximity Read

Cellular heterogeneity and dynamics of the human uterus in healthy premenopausal womenSemantic proximity Read

An integrated single-cell reference atlas of the human endometriumSemantic proximity Read

Stromal Heterogeneity in the Human Proliferative Endometrium—A Single-Cell RNA Sequencing StudySemantic proximity Read

Whole-tissue deconvolution and scRNAseq analysis identify altered endometrial cellular compositions and functionality associated with endometriosisSemantic proximity Read

Single-cell transcriptomic analysis of immune cell dynamics in the healthy human endometriumSemantic proximity Read