Article

An in silico reverse vaccinology approach to design a novel multiepitope peptide vaccine for non-small cell lung cancers

2023-01-01

Abstract excerpt

Non-small cell lung cancer (NSCLC) is the most prevalent and fatal lung cancer. The multiepitope vaccine is one of the immunotherapies successfully applied to treat NSCLC. We designed a multiepitope vaccine with MHC-I, MHC-II, CTL, and linear B cell epitopes of MAGE-A3, EGF, and MUC-1 oncoproteins employing in silico immunoinformatics approach. The structural assessment of the vaccine showed it as a well-stable pr...

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Literature Corpus work: d92b533a-aa03-5aca-b247-0e05b747a78b
DOI: 10.1016/j.imu.2023.101169

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