Article

Identification and evaluation of tumor pyroptosis-associated antigens for design a vaccine candidate against lung cancer

2024-11-05

Abstract excerpt

<title>Abstract</title> <p>Lung cancer is the leading cause of cancer-related mortality worldwide, necessitating the development of new treatment strategies. This study aims to design a novel multi-epitope vaccine targeting pyroptosis-associated proteins (CARD8, NAIP, NLRP1, and NLRP3) using immunoinformatics. T-cell and B-cell epitopes were identified from these proteins and assessed for antigenicity, non-toxici...

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Identifiers and source

Literature Corpus work: f447b836-1493-5210-875a-b1e767c41820
DOI: 10.21203/rs.3.rs-5329441/v1

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