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Article

Muscular dystrophy candidate gene FRG1 is critical for muscle development

18 Dec 2008

Abstract excerpt

The leading candidate gene responsible for facioscapulohumeral muscular dystrophy (FSHD) is FRG1 (FSHD region gene 1). However, the correlation of altered FRG1 expression levels with disease pathology has remained controversial and the precise function of FRG1 is unknown. Here, we carried out a detailed analysis of the normal expression patterns and effects of FRG1 misexpression during vertebrate embryonic...

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PMID: 19097195
DOI: 10.1002/dvdy.21830

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