Article

Smaller clinical trials for decision making; a case study to show p-values are costly

2018-09-27

Abstract excerpt

<h4>Background: </h4> Clinical trials might be larger than needed because arbitrary levels of statistical confidence are sought in the results. Traditional sample size calculations ignore the marginal value of the information collected for decision making. The statistical hypothesis testing objective is misaligned with the goal of generating information necessary for decision-making. The aim of the present study w...

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Literature Corpus work: d82be45e-4727-5a7d-8914-035750347f82
DOI: 10.12688/f1000research.15522.2

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