Article

miRNome profiling of lung cancer metastases revealed a key role for miRNA-PD-L1 axis in the modulation of chemotherapy response

2022-11-23

Abstract excerpt

<h4>ABSTRACT</h4> Locally-advanced non–small-cell lung cancer (NSCLC) is frequent at diagnosis and requires multimodal treatment approaches. Neoadjuvant chemotherapy (NACT) followed by surgery is the treatment of choice for operable locally-advanced NSCLC (Stage IIIA). However, the majority of patients are NACT-resistant and shows persistent lymph nodal metastases (LNmets) and an adverse outcome. Therefore, the i...

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Literature Corpus work: 05bef33c-69a1-5dd2-8a3a-f40989f1b0db
DOI: 10.1101/2022.11.23.517634

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