Article

<i>Cis</i> -vaccenic acid is a key product of stearoyl-CoA desaturase 1 and a critical oncogenic factor in prostate cancer

2024-03-30

Abstract excerpt

<h4>Summary</h4> Altered monounsaturated fatty acid (MUFA) metabolism is a hallmark of oncogenic transformation. Recently, the MUFA cis -vaccenic acid (cVA) was identified as a putative regulator of prostate cancer cell viability. cVA production requires the activity of stearoyl CoA desaturase 1 (SCD1), an enzyme frequently dysregulated in cancer, but the role of cVA in regulating cancer cell phenotypes has not...

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Literature Corpus work: d7d722b3-7a8f-595d-97a0-4548e0dc5483
DOI: 10.1101/2024.03.28.587238

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