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STK11 and KEAP1 mutations in non-small cell lung cancer patients: Descriptive analysis and prognostic value among Hispanics (STRIKE registry-CLICaP).

Lung cancer (Amsterdam, Netherlands) - 1 Aug 2022

Cordeiro de Lima Vladmir C, Corassa Marcelo, Saldanha Erick, Freitas Helano, Arrieta Oscar, Raez Luis, Samtani Suraj, Ramos Maritza, Rojas Carlos, Burotto Mauricio, Chamorro Diego F, Recondo Gonzalo, Ruiz-Patiño Alejandro, Más Luis, Zatarain-Barrón Lucia, Mejía Sergio, Nicolas Minata José, Martín Claudio, Bautista Blaquier Juan, Motta Guerrero Rodrigo, Aliaga-Macha Carlos, Carracedo Carlos, Ordóñez-Reyes Camila, Garcia-Robledo Juan Esteban, Corrales Luis, Sotelo Carolina, Ricaurte Luisa, Santoyo Nicolas, Cuello Mauricio, Jaller Elvira, Rodríguez July, Archila Pilar, Bermudez Maritza, Gamez Tatiana, Russo Alessandro, Viola Lucia, Malapelle Umberto, de Miguel Perez Diego, Rolfo Christian, Rosell Rafael, Cardona Andrés F

Abstract excerpt

BACKGROUND: Mutations in STK11 (STK11Mut) and, frequently co-occurring, KEAP1 mutations (KEAP1Mut) are associated with poor survival in metastatic Non-small Cell Lung Cancer (mNSCLC) patients treated with immunotherapy. However, there are limited data regarding the prognostic or predictive significance of these genomic alterations among Hispanics. METHODS: This retrospective study analyzed a cohort of Hispanic...

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PMID: 35753125
DOI: 10.1016/j.lungcan.2022.06.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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