Article

Design, synthesis, and biological evaluation of 1,8-naphthyridine derivatives as RSK4 inhibitors for the treatment of lung cancer

2018-01-01

Abstract excerpt

Lung cancer is the most common cause of cancer death worldwide and it has one of the lowest survival rates among tumours, thus the need to develop new drugs to treat the disease is clear. Among the different kinases involved in cancer pathologies in general, and in lung cancer, we focused our efforts on the validation of RSK4 as a tumour promoter in the lungs. Preliminary unpublished results suggested the antibiot...

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Literature Corpus work: d7bcd90c-255b-52ca-9905-051238104cfc
DOI: 10.25560/84677

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