Article

Dysbiosis of gut microbiota and resistome in antibiotic-treated paediatric Mycoplasma pneumoniae pneumonia: A 16S-metagenomics-metabolomics study

2025-06-09

Abstract excerpt

<title>Abstract</title> <p> This study systematically investigates the compositional and functional alterations in gut microbiota and their metabolic profiles among healthy children (Group C), Mycoplasma pneumoniae (MP)-infected pneumonia patients (Group MP), and cohorts treated with azithromycin (Group AC) or ceftriaxone (Group CE). Utilizing 16S rRNA gene sequencing, metagenomic sequencing, and metabolomics, w...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d719755f-e5b2-539a-9469-984115f63072
DOI: 10.21203/rs.3.rs-6551740/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Dysbiosis of gut microbiota and resistome in antibiotic-treated paediatric Mycoplasma pneumoniae pneumonia: A 16S-metagenomics-metabolomics studyDOI 10.21203/rs.3.rs-6551740/v1Read

Upper Airway Microbiota Dysbiosis and Immune Imbalance in Children with Refractory and Non-refractory Mycoplasma pneumoniae Pneumonia: A Cross-sectional StudySemantic proximity Read

An integrated respiratory microbial gene catalogue to better understand the microbial aetiology of Mycoplasma pneumoniae pneumoniaSemantic proximity Read

Alteration of the intestinal flora in children after antibiotic treatment explored using 16S rRNA sequencingSemantic proximity Read

Empiric Azithromycin in COVID-19 Impacts the Respiratory Microbiome and Antimicrobial Resistome without Anti-inflammatory BenefitSemantic proximity Read

Immunopathogenesis, molecular phenotyping, and host-directed interventions for severe pediatric Mycoplasma pneumoniae pneumonia in the post-pandemic era.Semantic proximity Read

Disease-associated gut microbiome and metabolome changes in patients with chronic obstructive pulmonary diseaseSemantic proximity Read

Resistome and microbiome-immune interactions in an Eastern European population with high antibiotic useSemantic proximity Read

Disruption of the Gut Ecosystem by AntibioticsSemantic proximity Read

Clinical Value of Metagenomics Next-Generation Sequencing in Antibiotic Resistance of a Patient with Severe Refractory Mycoplasma pneumoniae Pneumonia: A Case ReportSemantic proximity Read

Genomic and ecologic characteristics of the airway microbial-mucosal complexSemantic proximity Read

Exploring the effects of short-course antibiotics on children's gut flora by using 16S rRNA gene sequencing: a case-control studySemantic proximity Read

Exploring Alterations in the Gut Resistome in Medically Treated Inflammatory Bowel Disease PatientsSemantic proximity Read