Article

Upper Airway Microbiota Dysbiosis and Immune Imbalance in Children with Refractory and Non-refractory Mycoplasma pneumoniae Pneumonia: A Cross-sectional Study

2026-05-22

Abstract excerpt

<title>Abstract</title> <p>Objective Mycoplasma pneumoniae pneumonia (MPP) is a common respiratory infection in children, with refractory MPP (RMPP) showing poor response to macrolide antibiotics, prolonged course, and severe complications. This study aimed to investigate immune dysfunction and upper respiratory microbiota alterations in RMPP. Methods A cross-sectional study was conducted on 27 RMPP and 21 gene...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: de5998e2-f36e-5317-807b-cd1316f48f7e
DOI: 10.21203/rs.3.rs-9219059/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Upper Airway Microbiota Dysbiosis and Immune Imbalance in Children with Refractory and Non-refractory Mycoplasma pneumoniae Pneumonia: A Cross-sectional StudyDOI 10.21203/rs.3.rs-9219059/v1Read

Immune response plays a role in Mycoplasma pneumoniae pneumoniaSemantic proximity Read

Unravelling distinct patterns of metagenomic surveillance and respiratory microbiota between two P1 genotypes of Mycoplasma pneumoniaeSemantic proximity Read

Immunopathogenesis, molecular phenotyping, and host-directed interventions for severe pediatric Mycoplasma pneumoniae pneumonia in the post-pandemic era.Semantic proximity Read

Integrative study of pulmonary microbiome, transcriptome and clinical outcomes in Mycoplasma pneumoniae pneumoniaSemantic proximity Read

An integrated respiratory microbial gene catalogue to better understand the microbial aetiology of Mycoplasma pneumoniae pneumoniaSemantic proximity Read

Molecular epidemiology of Mycoplasma pneumoniae pneumonia in children, Wuhan, 2020-2022Semantic proximity Read

Differences in pulmonary microbiota of severe community-acquired pneumonia with different pathogenic microorganisms in childrenSemantic proximity Read

Bronchoalveolar lavage combined with metagenomic assessment of children hospitalized with Mycoplasma pneumoniae pneumoniaSemantic proximity Read

Metagenomic next-generation sequencing of bronchoalveolar lavage fluid from children with severe pneumonia in pediatric intensive care unitSemantic proximity Read

Characteristics of gut microbiota in 100 children with mycoplasma pneumonia in ChinaSemantic proximity Read

Metagenomic Next-Generation Sequencing of Bronchoalveolar Lavage Fluid From Children With Severe Pneumonia in Pediatric Intensive Care UnitSemantic proximity Read

Macrolide resistance and risk factors for refractory Mycoplasma pneumoniae pneumonia in pediatric patients from Wuhu, China: A retrospective cohort study.Semantic proximity Read