Article

Expression and Prognostic Significance of m6A-Related Genes in TP53-Mutant Non-Small-Cell Lung Cancer

2020-12-29

Abstract excerpt

<h4>Background: </h4> TP53 is an important tumor suppressor gene on human chromosome 17. TP53 mutations have been confirmed in more than 60% of tumor patients' somatic cells. N6-methyladenosine is an enzyme that plays an important role in mRNA splicing, translation, and stabilization. It is a common internal modification of nucleotides, that is regulated by methyltransferases ("writer"), binding proteins ("reader"...

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Literature Corpus work: d7104fea-ca25-5bf7-bd1c-56f449e5e2dc
DOI: 10.21203/rs.3.rs-127631/v1

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