Article

Expression and Prognostic Significance of m6A-Related Genes in TP53-Mutant Non-small-cell Lung Cancer

2020-12-11

Abstract excerpt

<title>Abstract</title> <p>BackgroundTP53 is an important tumor suppressor gene located on human chromosome 17. TP53 mutations have been confirmed in more than 60% of tumor patients' somatic cells. N6-methyladenosine is an enzyme that plays an important role in mRNA splicing, translation, and stabilization. It is a common internal modification of nucleotides, that is regulated by methyltransferases ("writer"), bi...

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Literature Corpus work: 0ae4c660-e5fc-5aed-81af-f4215bf65a83
DOI: 10.21203/rs.3.rs-125358/v1

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