Article

Proteomic profiling reveals KRT6C as the hereterodimer partner for KRT9 in epidermolytic palmoplantar keratoderma

2022-04-21

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Epidermolytic palmoplantar keratoderma (EPPK), a highly penetrant autosomal dominant genodermatosis, is characterized by diffuse yellow keratoses on the palms and soles, with distinct erythematous border. The keratin 9 gene (<italic>KRT9</italic>) is restrictedly expressed in the suprabasal layer of palmoplantar epidermis, whose mutations are responsible for EPP...

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Literature Corpus work: d7019301-d0c2-5c48-9086-8d091e4d9898
DOI: 10.21203/rs.3.rs-1544457/v1

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