Article
A novel mutation of keratin 9 in a large Chinese family with epidermolytic palmoplantar keratoderma.
The British journal of dermatology - 1 Apr 2004
He X-H, Zhang X-N, Mao W, Chen H-P, Xu L-R, Chen H, He X-L, Le Y-P
Abstract excerpt
BACKGROUND: Epidermolytic palmoplantar keratoderma (EPPK) is an autosomal dominant inherited skin disorder characterized by diffuse yellow thickening of the skin of the palms and soles, sharply bordered with erythematous margins. Histologically and ultrastructurally, EPPK presents cytolysis of keratinocytes and abnormal aggregation of tonofilaments in the suprabasal layers of the epidermis. To date, 15 different...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.