Article

Concordant and discordant gene expression signatures of twin placentas in the setting of preeclampsia

2025-08-16

Abstract excerpt

<h4>Background</h4> Multifetal pregnancies are associated with increased risk for preeclampsia (PreE), but the underlying pathogenesis may differ from singleton gestations. It remains unclear whether both placentas in twin pregnancies complicated by PreE exhibit molecular signatures of the disease simultaneously or in isolation. <h4>Methods</h4> We performed RNA sequencing on 32 individual placental samples from...

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Literature Corpus work: d6f6855b-a310-5ec2-91c4-3e05c653af42
DOI: 10.1101/2025.08.14.25333727

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