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Article

Co-alterations of circadian clock gene transcripts in human placenta in preeclampsia

25 Oct 2022

Abstract excerpt

Pre-eclampsia (PE) is a hypertensive condition that occurs during pregnancy and complicates up to 4% of pregnancies. PE exhibits several circadian-related characteristics, and the placenta possesses a functioning molecular clock. We examined the associations of 17 core circadian gene transcripts in placenta with PE vs. non-PE (a mixture of pregnant women with term, preterm, small-for-gestational-age, or...

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PMID: 36284122
DOI: 10.1038/s41598-022-22507-3

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