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The role of mitochondrial defects and oxidative stress in Alzheimer’s disease

18 Feb 2019

Abstract excerpt

Alzheimer's disease (AD) is a complex, progressive, and irreversible neurodegenerative disorder. Recent reports suggest that it affects more than 36 million people worldwide and accounts 60-80% of all cases of dementia. It is characterised by aberrations of multiple interactive systems and pathways, which ultimately lead to memory loss and cognitive dysfunction. The exact mechanisms and initial triggering factors...

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PMID: 30775938
DOI: 10.1080/1061186x.2019.1584808

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