Article

The Impact of Exogenous Tetrodotoxin on the piRNAs and mRNAs Profiles of Gonads in Pufferfish Takifugu Flavidus

2021-11-03

Abstract excerpt

<title>Abstract</title> <p>Tetrodotoxin (TTX) is a deadly neurotoxin and usually accumulates in large amounts in the ovaries but is non-toxic or low toxic in the testis of pufferfish. The molecular mechanism underlying sexual dimorphism of TTX accumulation in gonads is complex and unclear. Piwi/piRNA complexes are essential for germline specification, gametogenesis, and gonadal development, they also demonstrate...

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Literature Corpus work: d66a4c47-7a42-57e5-81a6-3f78a0850083
DOI: 10.21203/rs.3.rs-951626/v1

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