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Article

Intestinal bacterial indicator phylotypes associate with impaired DNA double-stranded break sensors but augmented skeletal bone micro-structure.

Carcinogenesis - 17 Jun 2020

Maier Irene, Liu Jared, Ruegger Paul M, Deutschmann Julia, Patsch Janina M, Helbich Thomas H, Borneman James, Schiestl Robert H

Abstract excerpt

Intestinal microbiota are considered a sensor for molecular pathways, which orchestrate energy balance, immune responses, and cell regeneration. We previously reported that microbiota restriction promoted higher levels of systemic radiation-induced genotoxicity, proliferative lymphocyte activation, and apoptotic polarization of metabolic pathways. Restricted intestinal microbiota (RM) that harbors increased...

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PMID: 31840161
DOI: 10.1093/carcin/bgz204
PMCID: PMC7456343

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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