Article
MiR-195 affects cell migration and cell proliferation by down-regulating DIEXF in Hirschsprung’s Disease
9 Jul 2014
Abstract excerpt
BACKGROUND: Hirschsprung's disease (HSCR) is the most common congenital gut motility disorder. We aimed to investigate the roles of miR-195 in the pathogenesis of HSCR. METHODS: In this study, we measured the expression levels of miRNA, mRNA, and protein in colon tissues from 78 patients with HSCR and 66 controls without HSCR. Transwell, Cell Counting Kit-8 (CCK-8) and flow cytometry assay were employed to detect...
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