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<i>Staphylococcus aureus</i> adopts revertible intracellular viable-but-non-culturable phenotypes in chronic osteocyte infections

2025-01-02

Abstract excerpt

Osteomyelitis associated with periprosthetic joint infection (PJI) is a serious and growing complication of orthopaedic joint replacement surgery, with a failure to cure rate within 2-years of between 15-46%. PJI is a severe chronic infectious disease with a 20% recurrence rate and culture-negativity in 7–39% of cases, of which 14–27% are PCR-positive, findings that remain poorly explained. Osteocytes, the most nu...

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Literature Corpus work
d59e66b3-5409-5dc3-87df-6ff46ce8cd22
DOI
10.1101/2024.12.17.629047
Open publication

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<i>Staphylococcus aureus</i> adopts revertible intracellular viable-but-non-culturable phenotypes in chronic osteocyte infectionsDOI 10.1101/2024.12.17.629047
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