Article
Adaptive processes of<i>Staphylococcus aureus</i>isolates during the progression from acute to chronic bone and joint infections in patients
26 Feb 2016
Abstract excerpt
Staphylococcus aureus bone and joint infection (BJI) is associated with significant rates of chronicity and relapse. In this study, we investigated how S. aureus is able to adapt to the human environment by comparing isolates from single patients with persisting or relapsing BJIs that were recovered during the initial and recurrent BJI episodes. In vitro and in vivo assays and whole-genome sequencing analyses...
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