Article

Network integration of multi-tumour omics data suggests novel targeting strategies

2017-06-05

Abstract excerpt

We characterize different tumour types in the search for multi-tumour drug targets, in particular aiming for drug repurposing or novel drug combinations. Starting from 11 tumour types from The Cancer Genome Atlas, we obtain three clusters based on transcriptomic correlation profiles. A network-based analysis, integrating gene expression profiles and protein interactions of cancer-related genes, allowed us to defin...

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Literature Corpus work: d59d919f-4fad-5a49-aa2c-ba80afa7880a
DOI: 10.1101/146209

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