Article

Unexpected predicted length variation for the coding sequence of the sleep related gene, <i>BHLHE41</i> in gorilla amidst strong purifying selection across mammals

2019-09-20

Abstract excerpt

There is a molecular basis for many sleep patterns and disorders involving circadian clock genes. In humans, “short-sleeper” behavior has been linked to specific amino acid substitutions in BHLHE41 (DEC2), yet little is known about variation at these sites and across this gene in mammals. We compare BHLHE41 coding sequences for 27 mammals. The coding sequence alignment length was 1794bp, of which 55.0% of base p...

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Literature Corpus work: d4e83fda-4cb3-5c1a-aeb9-971e58b677f3
DOI: 10.1101/773770

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