Article

Abnormal in LMNA Triggers a Shift in Intracellular Metabolic Homeostasis Via AMPK Activation

2022-07-18

Abstract excerpt

Laminopathies are a spectrum of diseases caused by LMNA mutations. In familial partial lipodystrophy of Dunnigan (FPLD), LMNA plays role in the differentiation and development of adipocytes and lipid metabolism. Changes in LMNA predict not only the differentiation of adipose-derived mesenchymal stem cells (AD-MSCs) but also the transformation of cancer cells. Hence, our in-depth study aimed to identify the molecul...

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Literature Corpus work: d4e640fd-2e02-5c04-a9b3-3a1857b41d15
DOI: 10.20944/preprints202207.0253.v1

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