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Article

The role of LMNA in adipose: a novel mouse model of lipodystrophy based on the Dunnigan-type familial partial lipodystrophy mutation.

Journal of lipid research - 1 Jun 2009

Wojtanik Kari M, Edgemon Keith, Viswanadha Srikant, Lindsey Brigette, Haluzik Martin, Chen Weiping, Poy George, Reitman Marc, Londos Constantine

Abstract excerpt

We investigated the role of LMNA in adipose tissue by developing a novel mouse model of lipodystrophy. Transgenic mice were generated that express the LMNA mutation that causes familial partial lipodystrophy of the Dunnigan type (FPLD2). The phenotype observed in FPLD-transgenic mice resembles ma...

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Share to Adipocytes
Share to Adipose Tissue
Share to Adipose Tissue, Brown

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fatty Liver

Share to Lamin Type A

Share to Lipodystrophy, Familial Partial

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Source

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Identifiers

PMID: 19201734
DOI: 10.1194/jlr.M800491-JLR200
PMCID: PMC2681389

Genes

LMNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19201734-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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