Article

Establishment of HLA class I and MICA/B null HEK-293T panel expressing single MICA alleles to detect anti-MICA antibodies

2021-05-03

Abstract excerpt

Pre- and post-transplantation anti-MICA antibody detection development are associated with an increased rejection risk and low graft survival. We previously generated HLA class I null HEK-293T using CRISPR/Cas9, while MICA and MICB genes were removed in this study. A panel of 11 cell lines expressing single MICA alleles was established. Anti-MICA antibody in the sera of kidney transplant patients was determined us...

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Literature Corpus work: d4dbac1b-ad57-59f0-9c1b-3280f18ba7a0
DOI: 10.21203/rs.3.rs-442120/v1

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