Article

Role of ALDH3A1 in Maintaining the Balance between Alveolar Type 1 and Type 2 Cells in Emphysema: From Patient to Organoid Model

2024-12-30

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Chronic obstructive pulmonary disease (COPD) is characterized by alveolar destruction, which is called emphysema. Alveoli are mainly composed of alveolar type 1 (AT1) and alveolar type 2 (AT2) cells; however, the specific mechanisms regulating AT1 and AT2 during the development of emphysema remain unclear. <bold>Methods: </bold>This study performed single-cell s...

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Literature Corpus work: d4562ed9-09ac-5c5e-9409-328301575367
DOI: 10.21203/rs.3.rs-5665061/v1

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