Decreased miRNA-148a-3p expression in skeletal muscle of patients with chronic kidney disease

Abstract excerpt

<h4>Introduction</h4> Skeletal muscle wasting is a common complication of chronic kidney disease which leads to a loss of muscle function. The pathogenesis of skeletal muscle wasting is incompletely understood, which is preventing the development of targeted therapeutics. Recent evidence implicates miRNAs in the of skeletal muscle wasting. Our aim was to firstly examine miRNA profiles of CKD human skeletal muscle...

Topics

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• Extracellular vesicles in disease
• High-Throughput Nucleotide Sequencing
• MicroRNAs
• Muscle Physiology and Disorders
• Muscle, Skeletal
• Muscle Strength
• Myosin Heavy Chains
• Principal Component Analysis

Identifiers and source

Literature Corpus work

d420149b-f30c-517f-823c-44b7c178de01

DOI

10.1101/2022.05.24.493194