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Feasibility of Known RNA Polymerase Inhibitors as Anti-SARS-CoV-2 Drugs

26 Apr 2020

Abstract excerpt

Coronaviruses (CoVs) are positive-stranded RNA viruses that infect humans and animals. Infection by CoVs such as HCoV-229E, -NL63, -OC43 and -HKU1 leads to the common cold, short lasting rhinitis, cough, sore throat and fever. However, CoVs such as Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV), Middle East Respiratory Syndrome Coronavirus (MERS-CoV), and the newest SARS-CoV-2 (the causative agent of...

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PMID: 32357471
DOI: 10.3390/pathogens9050320

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