Article

Plant-Derived Recombinant Macromolecular PAP-IgG Fc as A Novel Prostate Cancer Vaccine Candidate Eliciting Robust Immune Responses

2024-10-30

Abstract excerpt

<title>Abstract</title> <p>Prostatic acid phosphatase (PAP) is a specific protein that is highly expressed in prostate cancer. In this study, we constructed two recombinant PAP fusion genes: PAP fused to the immunoglobulin G (IgG) Fc fragment (designated PAP-Fc) and PAP-Fc fused to the endoplasmic reticulum retention sequence KDEL (designated PAP-FcK). Transgenic <italic>Nicotiana tabacum</italic> plants expressi...

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Literature Corpus work: d38ce10b-6021-586e-bbe0-7d66380cb6b0
DOI: 10.21203/rs.3.rs-5286242/v1

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