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Article

Clinical activity of MAPK targeted therapies in patients with non-V600 BRAF mutant tumors

2022-02-21

Abstract excerpt

<h4>Purpose</h4> Non-V600 mutations comprise approximately 35% of all BRAF mutations in cancer. Many of these mutations have been identified as oncogenic drivers in a wide array of cancer types and can be classified into three Classes according to molecular characteristics. Consensus treatment strategies for Class 2 and 3 BRAF mutations have not yet been established. <h4>Methods</h4> We performed a systematic revi...

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Literature Corpus work
d32116e8-5590-5568-9a76-b2255a080ff7
DOI
10.1101/2022.02.17.22271120
Open publication

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Clinical activity of MAPK targeted therapies in patients with non-V600 BRAF mutant tumorsDOI 10.1101/2022.02.17.22271120
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