Article

Calabria as a Genetic Isolate, a Model for the Study of Neurodegenerative Diseases

2022-08-22

Abstract excerpt

Although originally multi-ethnic in its structure, nowadays the Calabria region of southern Italy represents an area with a low genetic heterogeneity and a high level of consanguinity that allows rare mutations to be maintained due to the founder effect. A complex research methodology ranging from clinical activity to genealogical reconstruction of families/populations along the centuries, creation of databases, a...

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Literature Corpus work: d3132fbc-268f-5c13-b8cf-dfb944e38e2e
DOI: 10.20944/preprints202208.0383.v1

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